Advanced mode tools are handy for highly skilled users. Immunization prevents some problems by adjusting browser settings. Boot-time scan manages some locked files

Poor at real-world spyware removal. Real-time protection interferes with spyware removal and rarely identifies malware. Does almost nothing to prevent malware install on a clean system

Spybot's skill at cleaning up malware-infested systems is mediocre, and it has almost no ability to protect a clean system. Back in its heyday it was deservedly popular, but that day has long passed. For modern threats you'll need a modern spyware...